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Botulinum Toxin - 1 Vial x 150 IU
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| |  | | Package: 1 Vial x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | | | Price: $145.00 | |  | | |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is type-A toxin that encloses 150 IU in one vial and can be used into one patient. Botulinum Toxin Type A is a kind of preparation to correct light lines as well as shrink the face.
This product is a sterilized, lyophilized formula of cleansed botulinum toxin type A, formed from the crude toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium holding trypticase as well yeast extract. A series of cleansing practice were used to form a galssy complex consisting of the active high molecular weight toxin protein also an linked hemagglutinin. Once re-diluted and dialyzed the crystal clear toxin, an accurate quantity of the disinfected clarified (0.2 microns) toxin were added to a solution having gelatin-dextran-sucrose, and then lyophilized. Every vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This preparation is suggested for the dealing of blepharospasm, hemi facial contraction in adults and some categories of strabismus, specialy for acute paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy and strabismus which cannot be adjusted by surgery. Anti-Wrinkle, Thin looks also legs.
USAGE AND DOSING:
1. Place for inoculation:
- For blepharospasm: the inoculation should be injected intramuscularly at several locations of superior also inferior lids, i.e., using 4 to 5 places of inoculation into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other points on middle, lower face also cheek should be inserted intramuscularly. BTXA may be inserted at the places of two sides of eyebrow, upper lip or the lower jaw according to the illnesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is injected using a coaxial electrode syringe with electromyography direction or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into additional ocular muscles are selected agreeing to the form and point of strabismus.
2. Dosage:
150 IU must be watering into 2.0-2.5ml sterilized water before inserting.
Dilute with sterile normal saline according to different requests before administrating. The white loose product changes to be colorless or yellowish clear solution after the thinning.
- For blepharopasm also hemi facial spasm: the inoculation can be given following above advices. The primary measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the initial treatment is considered deficient one week later, a supplementary inoculation could be indicated. Dual dosing of 5 U / 0.1 ml could be given to recrudescent people. But the restriction of complete dosing of 55 U for 1 insertion and 200 U for 1 month must not be exceeded.
- For strabismus: for vertical and horizontal muscle strabismus of less than 20 prism diopters, the first measure into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial measure into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial dosage into each muscle is 2.5 U as well may be rised (to 5.0 each time) depending on the reply; for insistent VI cranial nerve paralysis lasted for more than 1 month. The injecting volume into ever muscle has to not more 0.1 ml. To patients, having insufficient result, extra insertion could be given. To recrudescent people, the dose may be repeated or increased irregularly. But for every muscle the extreme dosage must be less than 5 U / inj.
The Dissolving of BTXA (Botulinum Toxin Type A for Therapy):
The thinning of BTXA (Botulinum Toxin Type A for Therapy) with sterile normal saline should be done sensibly on the basis of real desires. Following is a reference table of thinning to be mentioned. The vial must be shaking quetly once adding sterile normal saline to the whole watering. The watering BTXA has to be administrated at once or stored in freezer at 2 to 8 degrees as well to be injected within 4 hours. The bottle also the syringe used with this product also the residual BTXA solution has to be prepared after sterilization.
UNEXPECTED EFFECTS:
Temporary ptosis of the eyelid, disadvantage of the inferior eyelid, minimized blinking, eyelid close in part, softness of face muscles, etc. can happen to a few people who used this medication remedy for blepharospasm as well hemi facial spasm. However, all the indications will vanish without any treatment within 3 to eight weeks. Passing and dissimilar degree of ptosis of the eyelid, vertical deviation as well infrequently mydriasis, which associated to the distribution of the toxin to the muscles adjacent, may occur to some people who take BTXA remedy for strabismus. The signs will vanish without any cure within a few weeks.
CONTRAINDICATIONS:
BTXA (Botulinum Toxin Type A for Therapy) is not suggested in persons with anaphylactic parts as well recognized aversion to this medicine.
NOTICES:
The insertion way must be suggested later to persons who have infection, grave infectious illness also prudently to the people with heart, liver, lung diseases, active tuberculosis, blood malady also pregnant women.
Botulinum toxin may be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of drugs must not be used during the treatment of BTXA.
BTXA is in minim reaction or without any reaction to the persons in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus provoked by extremely grave operation, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, bad muscle fiber contracture.
1:1000 adrenalines should be prepared in case of occasional accident.
SHELF LIFE:
Three years from the date of lyophilization. The action is clear and can be last 6 months.
KEEPING:
Keep at a temperature of -5 to -20 gr C (23 to -4 gr F). Store new vial at -5 temperatures.
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