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Botulinum Toxin - 5 Vials x 150 IU
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| |  | | Package: 5 Vials x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | | | Price: $470.00 | |  | | |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin which has 150 IU in one vial and can be prescribed into one person. Botulinum Toxin Type A is a type of preparation to correct small lines and shrink the look.
This injection is a disinfect, lyophilized form of purified botulinum toxin type A, produced from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium holding trypticase and yeast extract. A series of purifying practice were taken to form a clear complex consisting of the active high molecular weight toxin protein also an associated hemagglutinin. Once re-diluted and dialyzed the galssy toxin, an exact amount of the germ-free clean (0.2 microns) toxin were added to a solution containing gelatin-dextran-sucrose, and then lyophilized. Every vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This product is indicated for the cure of blepharospasm, hemi facial tremor in adults also some sorts of strabismus, mainly for grave paralytic strabismus, comitant strabismus, strabismus produced by endocrine myopathy also strabismus which cannot be adjusted through surgery. Anti-Wrinkle, Thin looks and legs.
USAGE AND DOSE:
1. Location for insertion:
- For blepharospasm: the injection has to be used intramuscularly at some locations of superior and inferior tops, i.e., taking 4 to 5 places of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the points mentioned above, three other points on middle, lower face and cheek have to be inserted intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) can be given at the places of two sides of eyebrow, upper lip or the lower jaw agreeing to the sicknesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is inoculated using a coaxial electrode syringe with electromyography supervision or amplifier under topical anesthesia of 0.5% Decarine. The injections into additional ocular muscles are selected according to the kind also lacation of strabismus.
2. Dosing:
150 IU have to be melting into 2.0-2.5ml sterilized water before inserting.
Melt with sterile normal saline agreeing to different requirements before inserting. The white loose product changes to be colorless or yellowish transparent solution after the reconstitution.
- For blepharopasm also hemi facial tremor: the insertion could be prescribed following above guidelines. The first dosing of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary dealing is considered insufficient 1 week later, an additional insertion may be indicated. Dual dosage of 5 U / 0.1 ml could be given to recrudescent people. But the restriction of complete dose of 55 U for one injection and 200 U for 1 month have to not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the initial measure into each muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dosage into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial dose into each muscle is 2.5 U as well can be rised (to 5.0 every) depending on the reply; for insistent VI cranial nerve paralysis lasted for more than 1 month. The inserting volume into each muscle has to not more 0.1 ml. To patients, having insufficient result, additional insertion can be indicated. To recrudescent people, the dosing may be repeated or amplified irregularly. But for each muscle the maximum measure should be less than 5 U / inj.
The Watering of BTXA:
The watering of this preparation with sterile normal saline must be prepared sensibly on the basis of real requirements. Following is a reference table of dilution to be recommended. The vial should be shaking mildly after adding sterile normal saline to the complete dissolving. The dilution BTXA (Botulinum Toxin Type A for Therapy) should be used at once or kept in refrigerator at 2 to 8 degrees and to be injected within 4 hours. The ampule also the needle used with this drug also the lasting BTXA solution should be disposed after purification.
UNEXPECTED REPLIES:
Temporary ptosis of the eyelid, drawback of the lower eyelid, reduced blinking, eyelid close partly, dimless of face muscles, etc. can occur to a number of people who take this medication therapy for blepharospasm as well hemi facial tremor. However, all the indications will go without any cure within 3 to 8 weeks. Temporary and different degree of ptosis of the eyelid, vertical deviance and infrequently mydriasis, which related to the distribution of the toxin to the muscles adjacent, may occur to some patients who used this preparation remedy for strabismus. The symptoms will disappear without any therapy within a few weeks.
CONTRAINDICATIONS:
BTXA is not indicated in people with anaphylactic structure as well identified allergic reaction to this product.
PRECAUTIONS:
The insertion process should be indicated later to people who have temperature, grave infectious malady and carefully to the individuals with heart, liver, lung diseases, active tuberculosis, blood diseases and pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medications should not be used during the administration of BTXA.
BTXA is in low effect or without any effect to the people in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus provoked by extremely modified surgery, chronic paralysis strabismus, as well as chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines should be prepared in case of occasional accident.
EXPIRATION:
Three years from the date of lyophilization. The effect is clear and may be last six months.
STORING:
Keep at a temperature of -5 to -20 gr C (23 to -4 gr F). Store unopened vial at -5 temperatures.
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